Difference between Pfizer and AstraZeneca

Difference between Pfizer and AstraZeneca: It has been a while since coronavirus hit the world. We are still experiencing it and none of the users understands when this pandemic will end. It has forced everyone to wear a mask, wash hands and maintain a physical distance of 2 meters apart. The economy of the state has greatly gone down and people have lost their loved ones’, businesses, jobs, etc.

However, the good thing is those scientists are always on their toes finding a vaccine that will help in reducing the spread of this virus. There are multiple vaccines made today. Among them include Pfizer & AstraZeneca. In this article, we are going to check out some of the differences between these two vaccines on various topics. Remember that both of the two vaccines are regarded to be safe in offering protection against corona.

What’s the AstraZeneca vaccine?

AstraZeneca, alias AZD1222 is a vaccine for COVID-19 developed by Oxford University & produced by Serum Institute. This vaccine consists of a dead virus understood as adenovirus, that’s the sapped version of the common cold virus which causes contaminations in chimpanzees. Thus, this virus transmits a small bit of the genetic code of the SARS-CoV-2 virus spike protein. After this vaccine is received, a surface spike protein is made, which prepares the immune system for attacking the SARS-CoV-2 virus.

Though, usage of the AstraZeneca vaccine is halted in some European countries due to the adverse results of this vaccine of blood clotting which raised serious concerns. UK’s medical regulator still states that it is completely secure for use. Reports of other patients who developed blood clots after they received the jab were explained. Due to this Germany, France, Italy, and other countries put a stop to this vaccination drive.

What is the Pfizer vaccine?

The Pfizer vaccine is an mRNA-based COVID19 vaccine that’s developed by American pharmaceutical huge Pfizer together with German-partner BioNTech. mRNA (messenger RNA) is a cutting-edge tech to make vaccines bulky & much quicker in comparison with other vaccine ways. The vaccine candidate isn’t made with the actual COVID-19 virus. It’s made using genetic material for spike protein that’s attached to a surface of the COVID-19 virus. Coronavirus forms copies of the virus by attaching the spikes to the host cell. The spikes are a possible target for vaccines.

Vaccine Efficacy

AstraZeneca – After injection of the first dose of the AstraZeneca vaccine, its efficiency is about 60 – 70 percent. Though after injection of the two doses, its efficiency goes up to about 90 percent. Thus, it’s a good idea for one to get both of the two doses as soon as possible & decrease the probability of getting coronavirus disease.

Pfizer – After the injection of this vaccine, its efficiency is 95 percent. This means that just there will be a 5 percent chance of you suffering from the coronavirus. This vaccine guards you against getting this disease to a superb extent. We hope that you will get your done of vaccination as quickly as possible.

Dose & Storage

AstraZeneca vaccine is stored & transported at standard temperatures & they are stored safely for about 6 months between 36 & 46-degrees Fahrenheit. As with dosage, the commended dosage is 2 intramuscular injections each of 0.5 ml. The interval between the two intramuscular injections should be 8 – 12 weeks separate.

Pfizer vaccine is also a two-dose injection that’s administered like intramuscular injections using 0.3 ml in every injection and the interval between the two doses should be three weeks. Therefore, if the 1st dose was on Date 1, then the 2nd dose should be scheduled to be on Date 22. With storage, the Pfizer vaccine needs to be kept at a temperature of sub-zero before they’re ready to be used.

Side Effects

Pfizer – About Pfizer’s side effects, you can have an infection on the injection site. One may also have redness, swelling, and pain in the injected arm. Some of the effects to the entire body include fatigue, & muscle aches. Inflammation can be everything. Remember the side effect isn’t necessarily similar to every person.

AstraZeneca – Side effects of the AstraZeneca vaccine are the same as those of Pfizer. However, the side effect of the vaccine begins after the first dose.

After getting the first dose, you can have swelling on the injection spot, redness, tenderness, muscle ache, allergies, fatigue, and one can also affect your whole body. The effects are nearly similar for any person, but there’s nothing to lose because the effects stop after a few days.



The CDC says that people that have underlying health states can receive the COVID-19 vaccine. This is as long as they have not had an earlier serious allergic reaction to a vaccine or anything with similar ingredients.

This includes individuals that have weakened immune systems or are breastfeeding or pregnant. Particular safety information for these people is limited, though increasing confirmation indicates that the vaccination poses less danger.

All of the ingredients utilized in the Pfizer-BioNTech vaccine are listed in the FDA fact-sheet that’s meant to be utilized by people giving & receiving a vaccine.


People that have allergic reactions to earlier vaccines can still get the AstraZeneca vaccine. If they have had earlier allergic reactions to the AstraZeneca vaccine or any of its ingredients they are advised to take a different vaccine.

People who have weak immune systems can be vaccinated using the AstraZeneca vaccine. As of now, no safety concerns that been reported. But the immune response to COVID-19 following vaccination can be weaker compared to that of another person who has a stronger immune system.

People that have had blood-clot along with some low count platelet brought by the previous dose of the AstraZeneca vaccine shouldn’t receive the vaccine.

People that are breastfeeding or pregnant can receive the AstraZeneca vaccine. However, talk with your health professional before receiving the vaccination.


Both of these COVID19 vaccines are helpful to prevent corona. Just receive your vaccination as soon as possible to prevent the spread of this virus as early as possible. Those that are already vaccinated are safe & their chances of getting this disease are minimal.

Latest Notifications

Leave a Reply

Your email address will not be published.